Pharma/Biopharma Challenges

The manufacturers of pharmaceutical and biopharmaceutical products must confront and overcome three main challenges to “control the controlled environments” within their operations:

1. Product Containment During pharma/biopharma production activities, even the smallest spill or leak incident involving common tap water has the potential to trigger a plant shutdown, with the resulting downtime and cleanup, remediation, sanitization and revalidation costs affecting not only the production schedule, but the operation’s overall bottom line. So, whether the fluid is water or ethylene glycol used in a chiller system, or various types of chemicals and solvents used in production processes, attaining and maintaining reliable, risk-free product containment is a top-of-mind concern for facility and operations managers.
2. Consistent Flow Rates As they say, “time is money” and with the high volume of fluids that enter the production facility, consistent, turbulence-free flow rates must be achieved and maintained if the manufacturing operation is to meet the needs of strict budgetary demands and production schedules.
3. Easy and Reliable Equipment Operation The couplers used to connect the array of high-purity hoses that are used to deliver fluids to storage tanks and production lines must be easy to connect and disconnect – with minimal physical strain placed on the operator – and robust enough to handle daily abuse and the thousands of connect/disconnect cycles that are performed during the coupler’s lifespan.